Author: bibhuti

A collaborative research team has uncovered a previously unknown mechanism of action of yaku’amide B, a structurally complex peptidic natural product derived from deep-sea sponge found in the waters near Yakushima Island, Japan. Natural products often exhibit multifaceted biological activities due to their structural complexity, interacting transiently with multiple biomolecules. Yaku’amide B was previously shown to inhibit ATP synthase, an essential enzyme for cellular energy production. However, this alone could not fully explain its unique anticancer properties. Source link

Saturday 14 March 2026 3:24 pm  |  Updated:  Saturday 14 March 2026 3:25 pm Trump has called for Starmer’s help. (Image: Getty Images) President Trump has called on Sir Keir Starmer to help secure the Strait of Hormuz, the critical stretch of water near Iran for a fifth of the world’s global oil supply. In a post on Truth Social, Trump demanded that China, France, Japan, South Korea and the UK send war ships to the region to stop it being under threat from Iranian missiles. “Many countries, especially those who are affected by Iran’s attempted closure of the Hormuz Strait, will be…

In recent years, people have been increasingly looking for new ways to form platonic connections, as loneliness and social isolation have become more prevalent. In 2023, the U.S. Surgeon General went so far as to label this issue a public health crisis. Remote workers, who miss the everyday interactions found in an office, and younger individuals eager to create their adult social circles based on shared interests and hobbies, are among those seeking meaningful friendships. Thanks to online dating apps, the stigma associated with finding connections online has largely faded away. This has welcomed a new wave of apps focused…

Part of a busy Glasgow road is currently closed amid an ongoing ‘police incident’. Source link

NIFRS confirmed that they are in attendance at the sceneRob Currell Live news reporter16:04, 14 Mar 2026Updated 16:10, 14 Mar 2026Northern Ireland Fire and Rescue Service stock image(Image: Justin Kernoghan/Belfast Live)Delays are currently being experienced on Kennedy Way in Belfast as Northern Ireland Fire and Rescue Service personnel deal with a car fire.The blaze is now reportedly under control on the road which took place heading from the motorway towards Andersontown Road.A spokesman from NIFRS said: “One appliance has attended from Cadogan Station. NIFRS is still in attendance at the moment.”READ MORE: Free street parking on St Patrick’s Day announced…

I get it; it’s not an easy time for a legacy automaker to be selling electric vehicles, what with incentives being gutted and Chinese automakers knocking at the door. But Honda is taking it to another level. This week, Honda killed its paltry — and frankly unpromising — EV programs. What little motivation Honda had to compete in the EV arena is apparently gone, and along with it, any chance of surviving the current wave of disruption that’s sweeping the industry. The company casts blame on U.S. tariffs and Chinese competition, two easy targets. But it never really had a viable EV…

The Bitcoin price has outperformed gold, silver, and major U.S. equity indexes since the outbreak of the Iran–Israel conflict escalation 2026, climbing above $73,000 even as oil surged and expectations for near-term interest rate cuts faded. Market data shows Bitcoin price rising about 8% since the first strikes against Iran, reaching a one-month high above $73,000. The move placed the digital asset ahead of several traditional safe-haven and risk assets during a period of geopolitical stress. Gold declined during the same stretch, falling roughly 3% from levels seen before the conflict began. Silver dropped more than 10%, sliding from above…

Five hundred women took part in The Big Swim today on Brighton beach, marking International Women’s Day, which took place last week. Swimmers gathered by Sea Lanes from around midday, as the colourful and lively atmosphere built up in anticipation of the swim. Event organiser Nicky Chisholm, centre, as goes by Pink Nicky (Image: The Argus) After warming up by dancing to the Bee Gees’ iconic tune More Than a Woman, participants lined up for a massive group photo just after 1pm. A conch shell was blown ceremoniously to honour Mother Nature, as part of an “ocean offering”, and then the…

Gillingham’s trip to high-flying Cambridge United only added to their woes after they were thrashed again.It was their former manager Neil Harris’ current side who this time proved too good for a Gills team lacking at both ends of the pitch. Dom Ball and Louis Appere scored first-half goals for a dominant Cambridge United. Sullay Kaikai added a quickfire double shortly after the restart and Shayne Lavery made it 5-0.Gillingham manager Gareth Ainsworth Picture: Barry GoodwinPrior to the match, the Gills chairman had urged patience from fans, while the official supporters’ club had pleaded for less abuse from the stands.Gillingham…

Meta is considering major layoffs that could affect 20% or more of the company’s workforce, according to Reuters. These layoffs could help the Facebook parent company offset its aggressive spending on AI infrastructure, as well as AI-related acquisitions and hiring. Meta employed nearly 79,000 people as of December 31, according to a recent filing. TechCrunch has reached out to Meta for comment. A company spokesperson told Reuters that its story was “speculative reporting about theoretical approaches.” The report comes as many tech companies — most recently Block — have announced sweeping layoffs that they say are necessary as AI automates…