The best AI startups in Australia in 2025 show that innovation happens when you combine domain knowledge, a strong vision, and the ability to solve real-world problems. These companies show a wide range of industry leadership and innovation from healthcare to food supply chains to climate risk modelling. This ecosystem is something that investors and partners who want to see real change should keep an eye on.
What Is An AI Startup?
An AI startup is a company that focuses on developing and implementing artificial intelligence technologies to create products or services. These startups use AI to meet the needs of different businesses and solve tough problems in a variety of fields.
Is AI in Demand in Australia?
Between 2025 and 2030, jobs in AI and machine learning will grow the fastest. Australia is the fifth best country in the world for using AI, and the number of jobs is expected to grow six times. According to the Tech Council of Australia (TCA), AI could create as many as 200,000 jobs in Australia by 2030.
What Are The Top 5 AI Startups in Australia?
In 2025 it is obvious that in the world of startups, Australia is a country not to be underestimated. These companies are changing the way businesses around the world use AI.
For investors, clients, and partners, Australia is now a strong contender in AI. It’s a centre for focused innovation that has an effect on the real world. That’s why its AI scene will be one to watch in 2025 and going forward. Although Australia already has many AI startups, some of the to AI startups in Australia include Leonardo.ai, Harrison.ai, Lumachain, Presagen and Reask.
Leonardo.ai
Leonardo.ai is generative AI for visual creativity. Based in Sydney Leonardo.ai has become a world leader in generative AI, making hyperrealistic images and videos possible. Since it went live in December 2022, the platform has made more than 700 million images, doubled the number of users to almost 30 million, and released an enterprise product called Leonardo for Teams.
Canva bought Leonardo.ai in the middle of 2024, but it still runs independently. It powers Canva’s Magic Studio suite with its own foundational model Phoenix and its real-time generation engine Flow State. It helps professionals in marketing, design, architecture, and entertainment by giving them scalable and legal AI tools that protect their copyright.
Harrison.ai
Harrison.ai is AI Diagnostics Transforming Healthcare. Harrison.ai, which is also based in Sydney, is a leader in medical imaging AI. It makes tools that help radiologists and pathologists all over the world. Its radiology solution can find up to 124 clinical findings in chest X-rays in less than 20 seconds, with a 45% increase in diagnostic accuracy. It is used by more than 1,000 healthcare facilities on five continents. techcrunch.com and startupscaleup.com.au
Harrison.ai got additional funding in early 2025. That money will help the company grow into the U.S., U.K., and Asia. It will also help pay for new products like Franklin.ai for pathology and next-gen chat-based image interpretation tools.
Lumachain
Lumachain is AI + Blockchain for Ethical Food Supply. Somali-Australian entrepreneur Jamila Gordon started Lumachain to use computer vision and blockchain to make food and meat processing supply chains safer, more efficient, and easier to track. Their platform has five main modules: safety, yield, quality, efficiency, and traceability. It also supports compliance with ethical and ESG standards around the world.
Presagen
Presagen is a startup that has to do with AI for IVF and Fertility Diagnostics. Presagen is all about using AI to help with fertility care. Life Whisperer, its main product, uses AI to check embryos during IVF. This makes it about 30% better at predicting the success of a pregnancy than traditional embryologist methods. The platform is already being used in clinics in Australia, the U.S., New Zealand, and Malaysia. The company wants to use its model for more than just IVF Presagen in the field of healthcare imaging diagnostics.
Reask
Reask is an AI-powered climate Risk & Catastrophe Modelling startup. Reask, which is based in Sydney, makes machine-learning models to predict extreme weather and the risk of natural disasters. Its tools give insurers, governments, and businesses high-resolution maps of disasters, probabilistic models of hazards, and information on how to respond to events. The company helps banks and other financial institutions plan for weather-related losses and build resilience.
What Sets These Startups Apart?
These startups differ from general AI startups. These types of AI learn from data that is only useful for their industry, so they don’t waste time on things that are irrelevant. That helps them understand the field’s context, terms, and logic much better than generic AI. And for some fields, this knowledge could be very important.
Different Sectors, Real-World Impact
Australia’s AI scene is made up of industry specific AI models, not generic AI apps. These include healthcare, agriculture, creative industries, and disaster resilience.
Strong Funding & International Reach
Harrison.ai and Leonardo.ai are two examples of startups that have raised tens of millions of dollars and are now expanding into the US, UK, APAC, and EU markets.
Ethical Design and Purpose-Driven Models
Along with innovation, companies like Lumachain and Presagen stress the importance of traceability, transparency, and social impact.
