The work will affect trains on Saturday (December 7) and Sunday (December 8).
We have compiled all of the details on these works so that you can plan your journey this weekend.
Saturday and Sunday (December 7 and December 8):
Engineering work is taking place overnight between Margate and Ramsgate, closing all lines.
The 11.10pm train on Saturday and 12.10am train on Sunday from London Victoria to Ramsgate via Chatham trains will be replaced by buses between Margate and Ramsgate.
Sunday (December 8):
Engineering work is taking place between Tunbridge Wells and Battle, closing all lines.
Trains will only be able to run between London Charing Cross and Tunbridge Wells.
Additional trains will run between Battle and Hastings.
Replacement buses will run between:
Tunbridge Wells and Battle calling at Wadhurst and Robertsbridge only
Tunbridge Wells and Battle calling at all stations
Sunday (December 8):
Engineering work is taking place between St Johns, Hither Green and Dartford closing the lines between Lewisham and Orpington, and between Lewisham and Dartford via Sidcup.
Paddock Wood Line: Trains between London Charing Cross and Ramsgate and Dover Priory via Tonbridge will be diverted to run to and from London Victoria.
These trains will only run between London Victoria and Minster via Dover Priory and Tonbridge and Ashford International via Tonbridge because of further engineering work.
Hastings Line: Trains between London Charing Cross and Hastings will be retimed and diverted via an alternative route between London Bridge and Orpington.
These trains will only run between London Charing Cross and Tunbridge Wells because of further engineering work.
Grove Park Line: Trains between London Charing Cross and Sevenoaks will not run.
Bromley South Line: Trains between London Victoria and Orpington will be extended to run to and from Sevenoaks.
Sidcup Line: Trains which usually only run between London Charing Cross and Dartford via Sidcup will not run.
Trains between London Charing Cross and Gravesend via Sidcup will be diverted to run via Bexleyheath calling at all stations between Lewisham and Dartford.
Replacement buses will run between:
Lewisham and Orpington
Lewisham and Dartford via Sidcup
Sunday (December 8):
Engineering work is taking place between Minster, Margate and between Sandwich and Ramsgate, closing all lines.
Trains between London Victoria and Ramsgate via Canterbury West will only run between London Victoria and Ashford International These trains will run to and from London Victoria because of further engineering work.
Trains between London Victoria and Dover Priory via Tonbridge will be extended to run to and from Minster via Sandwich and Dover Priory.
These trains run to and from London Victoria because of further engineering work.
These trains will detach and attach a portion of coaches at Ashford International which will run between Ashford International and Minster calling at all stations via Canterbury West.
Trains between London Victoria and Ramsgate via Chatham will only run between London Victoria and Margate.
Trains between London St Pancras International and Margate via Canterbury West will be retimed and only run between London St Pancras International and Minster.
Trains between London St Pancras International and Ramsgate via Dover Priory will only run between London St Pancras International and Dover Priory.
Trains between London St Pancras International and Ramsgate via Faversham will only run between London St Pancras International and Margate.
Replacement buses will run between:
Minster and Margate calling at Thanet Parkway, Ramsgate and Broadstairs
Minster and Ramsgate nonstop
Margate and Ramsgate calling at Broadstairs only
Margate and Ramsgate calling at all stations