Peter Paterson was last seen by his family members at around 5.30pm on Sunday, June 16 in the Hamilton area.
Cops are now searching for the 41-year-old and are urging anyone who may have seen him to get in touch.
He is described as white, 6ft 2in, of slim build with short brown hair.
When last seen, he was wearing a green and white Celtic football top, dark joggers and black Nike trainers.
He has a tattoo on his right forearm.
Peter has connections to the Tayside area however it is not known if he has travelled there.
If you have any information that can assist in tracing Peter, please contact Police Scotland on 101 quoting incident number 3696 of 16/06/24.