The discovery comes after a warrant was executed in Curzon Street in Ruchill on Friday, October 4 by officers from the Serious and Organised Crime Unit which resulted in a significant quantity of Class A drugs and a firearm being seized.
This included more than 90kg of cocaine, 23kg of heroin, 19kgs of MDMA and around 5800 diazepam and ecstasy tablets.
A quantity of cash and ammunition was also recovered.
A further 20kgs of cocaine was found in a vehicles.
The drugs have an estimated street value of £5.5million.
Two men, aged 30 and 45, and a 31`-year-old woman have been arrested and charged in connection.
They are due to appear at Glasgow Sheriff Court on Monday, October 7.
Detective Superintendent Steven Elliott said: “This very significant recovery sends a clear message that we will not tolerate illegal drugs in our communities.
“We are determined to protect the public from this harmful criminality by disrupting the cultivation and sale of illegal substances, preventing them being circulated on the streets of Scotland and addressing the concerns of local people.
“This action underlines our commitment to the Serious Organised Crime Taskforce and the country’s Serious Organised Crime Strategy.
“Information from the public is absolutely crucial to our work and we ask anyone with knowledge about drugs activity in their area to contact Police Scotland on 101.
“Alternatively, Crimestoppers can be contacted on 0800 555 111, where anonymity can be maintained.”
