In a statement, Buckingham Palace confirmed that King Charles had been diagnosed with a form of cancer.
The disease, which is not prostate cancer, was discovered while the King was being treated in hospital for an enlarged prostate.
The Palace has not confirmed the type of cancer.
Councillor Bella Sankey, leader of Brighton and Hove City Council, said: “I am so sorry to hear of His Majesty’s cancer diagnosis.
“On behalf of Brighton and Hove City Council, I extend my best wishes to the King for his successful medical treatment and his swift and full recovery.”
East Worthing and Shoreham MP Tim Loughton also joined others in offering his prayers for a speedy recovery.
He said: “Our prayers this evening are with His Majesty the King, whose thoughts are always on duty and the well-being of his people even during these worrying times.
“I am sure the people of Adur and Worthing join me in sending him our very best wishes for a speedy recovery.”
In a post on X, formerly Twitter, Wealden MP Nus Ghani said: “May HRH King Charles have a swift recovery and get well soon.”
Prince Harry, the Duke of Sussex, is expected to fly out to the UK in the coming days to see his father.
A source close to the duke confirmed that he has spoken to the King about his diagnosis.
The King has already started a schedule of regular treatments and is said to be receiving expert medical care from a specialist team, but has been advised to postpone public-facing duties.
Charles will, however, carry on working behind the scenes on his state business and official papers.
He returned from Sandringham to London earlier today to commence treatment as an out-patient.
The King has rearranged or postponed his forthcoming public engagements, but it is understood to be too early to say when he may return to full public duty, although he is said to be looking forward to doing so as soon as possible.
The statement from Buckingham Palace said: “During The King’s recent hospital procedure for benign prostate enlargement, a separate issue of concern was noted.
“Subsequent diagnostic tests have identified a form of cancer.
“His Majesty has today commenced a schedule of regular treatments, during which time he has been advised by doctors to postpone public-facing duties.
“Throughout this period, His Majesty will continue to undertake State business and official paperwork as usual.
“The King is grateful to his medical team for their swift intervention, which was made possible thanks to his recent hospital procedure.
“He remains wholly positive about his treatment and looks forward to returning to full public duty as soon as possible.
“His Majesty has chosen to share his diagnosis to prevent speculation and in the hope it may assist public understanding for all those around the world who are affected by cancer.”
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